In my experience, all three of these products work beautifully for the nasolabial folds, also called the parentheses lines, extending between the edges of the nostrils and the corners of the mouth. The primary difference between them is that Restylane and Juvederm are have a shorter duration (~ 6-9 months) as compared with Radiesse, which can last up to 18 months or longer. I have not found a
difference in duration between Restylane and Juvederm. The advantage of these hyaluronic acid (HA) fillers is that they can be dissolved with a simple injection of hyaluronidase in the unlikely event of a lump or asymmetry. Radiesse cannot be dissolved and is slightly more expensive at our center. I have not found a difference in the degree of bruising with any of these fillers
